Comparison of the interactions of daunorubicin in a free form and attached to single-walled carbon nanotubes with model lipid membranes

• Dorota Matyszewska

Beilstein J. Nanotechnol. 2016, 7, 524–532, doi:10.3762/bjnano.7.46

• Dorota Matyszewska Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Żwirki i Wigury 101, 02089 Warsaw, Poland 10.3762/bjnano.7.46 Abstract In this work the interactions of an anticancer drug daunorubicin (DNR) with model thiolipid layers composed of 1,2

• aspect in terms of side effects of the drug. Keywords: daunorubicin (DNR); 1,2-dipalmitoyl-sn-glycero-3-phosphothioethanol (DPPTE); drug carriers; model lipid membranes; single-walled carbon nanotubes (SWCNTs); Introduction Daunorubicin (DNR) is an anthracycline antitumor drug, which finds application

• nanotubes as drug delivery systems. Structures of daunorubicin (DNR) and 1,2-dipalmitoyl-sn-glycero-3-phosphothioethanol (DPPTE) used as a component of model membranes and single-walled carbon nanotubes modified with daunorubicin (SWCNTs-DNR). Surface pressure-area per molecule (π–A) isotherms of DPPTE